Markets

High Risk Patients

An estimated 15 million surgical patients and 3 million intensive care patients worldwide could benefit from accurate, less-invasive CO monitoring. In a survey of hundreds of American and European anesthesiologists, more than 90% indicated that their current operative fluid management could be improved, yet approximately 60% indicated that current cardiac output monitoring was too invasive or unreliable.

The total hospital market, including Emergency Rooms, approaches $1 Billion. In March 2011, the National Institute of Health and Clinical Excellence (NICE) of the UK published a guidance that recommended the use of cardiac output monitoring for fluid optimization to reduce complications, length of stay in the ICU and hospital readmissions. With full implementation of this approach, they estimated that the British National Health System alone could save at least £400 million annually.

Patients who can benefit from advanced hemodynamic monitoring for improved diagnosis and optimization of fluid and drug administration include:

High-risk and medium-risk surgeries:

• Cardiac Surgery
• Neuro Surgery
• Transplants, GI surgeries
• Pediatrics

Patients who have the following conditions or co-morbidities:

• Heart failure
• Hypertension
• COPD
• Renal Failure
• Sepsis
• Burns
• Trauma
• Multi-organ failure
• Acute Respiratory Distress Syndrome

Additional potential market segments include emergency department, first responders, military, and management of heart failure and hypertension patients. Customers in each of these segments can benefit from the Company's core value proposition of providing accurate, real-time detection of changes in blood flow and blood volume. For example, hemorrhage and resulting shock is the leading cause of death (50%) in the battlefield. To prevent these deaths, it is critical to identify signals such as cardiac output that will be altered during the earliest time period of blood volume loss. 

According to Kalorama, the U.S. patient monitoring market is currently $6 billion and it will grow at a 26% CAGR to reach $15 billion by 2015. This rapid growth is caused by several factors:

  1. A rapidly aging population leading to increasing patient numbers
  2. Cost-containment measures preventing a corresponding increase in clinical staff
  3. Medicare’s decision not to reimburse hospitals for treating costly complications

Each of these factors contributes to an increased emphasis on early detection, diagnosis, and precise treatment of critical conditions. Increased patient monitoring is an ideal way to achieve this goal.

References:

Wiener RS, Welch HG. Trends in the use of the pulmonary artery catheter in the United States, 1993-2004. JAMA, 298:423-429, 2007.

The Critical Care Workforce: A Study of the Supply and Demand for Critical Care Physicians. Available: http://bhpr.hrsa.gov/healthworkforce/reports/criticalcare/cc3.htm.

Fleming KC, Evans JM, Chutka DS. Caregiver and clinician shortages in an aging nation. Mayo Clin Proc, 78:1026-1040, 2003.

Pearse RM, Harrison DA, James P, Watson D, Hinds C, Rhodes A, Grounds RM, Bennett ED. Identification and characterisation of the high-risk surgical population in the United Kingdom. Crit Care, 10:R81, 2006.

Cannesson M, Pestel G, Ricks C, et al. Hemodynamic monitoring and management in patients undergoing high risk surgery: a survey among North American and European anesthesiologists. Critical Care, 2011;15(4):R197.

 

http://www.publications.parliament.uk/pa/cm201012/cmselect/cmhealth/1499/1499vw22.htm

 

http://www.nice.org.uk/nicemedia/live/13014/50988/50988.pdf

 

Society of Critical Care Medicine. Critical Care Statistics in the United States, 2006. Available: http://www.sccm.org/AboutSCCM/Public%20Relations/Pages/Statistics.aspx.